RESUMO
Abstract Objective: To analyze the morphofunctional regeneration process of facial nerve injury in the presence of insulin-like growth factor-1 and mesenchymal stem cells. Methods: Fourteen Wistar rats suffered unilateral facial nerve crushing and were randomly divided into two groups. All received insulin-like growth factor-1 inoculation, but only half of the animals received an additional inoculation of mesenchymal stem cells. The animals were followed for 90 days and facial nerve regeneration was analyzed via spontaneous facial motor function tests and immunohistochemistry in the nerve motor nucleus. Results: The group that received the growth factor and stem cells showed a statistically superior mean in vibrissae movements (p<0.01), touch reflex (p = 0.05) and eye closure (p<0.01), in addition to better immunohistochemistry reactivity. There was a statistically significant difference in the mean number of cells in the facial nerve nucleus between the experimental groups (p = 0.025), with the group that received the growth factor and stem cells showing the highest mean. Conclusion: The association between growth factor and stem cells potentiates the morphofunctional regeneration of the facial nerve, occurring faster and more effectively. Level of Evidence: 4, degree of recommendation C.
RESUMO
OBJECTIVE: To analyze the morphofunctional regeneration process of facial nerve injury in the presence of insulin-like growth factor-1 and mesenchymal stem cells. METHODS: Fourteen Wistar rats suffered unilateral facial nerve crushing and were randomly divided into two groups. All received insulin-like growth factor-1 inoculation, but only half of the animals received an additional inoculation of mesenchymal stem cells. The animals were followed for 90 days and facial nerve regeneration was analyzed via spontaneous facial motor function tests and immunohistochemistry in the nerve motor nucleus. RESULTS: The group that received the growth factor and stem cells showed a statistically superior mean in vibrissae movements (pâ¯<â¯0.01), touch reflex (pâ¯=â¯0.05) and eye closure (pâ¯<â¯0.01), in addition to better immunohistochemistry reactivity. There was a statistically significant difference in the mean number of cells in the facial nerve nucleus between the experimental groups (pâ¯=â¯0.025), with the group that received the growth factor and stem cells showing the highest mean. CONCLUSION: The association between growth factor and stem cells potentiates the morphofunctional regeneration of the facial nerve, occurring faster and more effectively. LEVEL OF EVIDENCE: 4, degree of recommendation C.
Assuntos
Lesões por Esmagamento , Traumatismos do Nervo Facial , Células-Tronco Mesenquimais , Ratos , Animais , Traumatismos do Nervo Facial/metabolismo , Ratos Wistar , Nervo Facial , Fator de Crescimento Insulin-Like I/metabolismo , Fator de Crescimento Insulin-Like I/farmacologia , Células-Tronco Mesenquimais/metabolismo , Lesões por Esmagamento/metabolismo , Regeneração Nervosa/fisiologiaRESUMO
Objetivo: identificar as práticas mais comuns atualmente utilizadas em Educação em Saúde desenvolvidas pelos profissionais da Estratégia Saúde da Família (ESF). Método: revisão integrativa, com vistas a responder a questão << Quais são as práticas de ES desenvolvidas pelos profissionais da ESF? >> realizada na LILACS e SciELO, em março de 2014, por meio dos descritores controlados em ciências da saúde: "educação, saúde e informação", contemplando seis etapas. Resultados: foram encontrados 365 artigos e após a aplicação dos critérios de inclusão e exclusão restaram quatro. Nessas publicações foram mencionadas como prática de educação em saúde palestras, ações em eventos festivos, criação de grupos de convivência e práticas corporais, orientações sobre cuidados com doenças crônicas e durante a gestação.(AU)
Objective: identifying the most common practices currently used in Health Education developed by the professionals of the Family Health Strategy (FHS). Method: an integrative review, with a view to answering the question << What are the Health Education practices developed by professionals of the FHS? >> Held in LILACS and SciELO in March 2014 by means of controlled descriptors in health sciences: "education, health and information", comprising six stages. Results: there were found 365 articles and after applying the inclusion and exclusion criteria remained four. These publications mentioned as a practice of health education lectures, actions in festive events, creation of community groups and bodily practices, guidelines about caring for chronic diseases and during pregnancy.(AU)
Objetivo: identificar las prácticas más comunes que se utilizan actualmente en la Educación en Salud desarrollada por los profesionales de la Estrategia de Salud de la Familia (ESF). Método: es una revisión integradora, con el fin de responder a la pregunta << ¿Cuáles son las prácticas de Educación en Salud desarrolladas por los profesionales de la ESF? >> Celebrada en LILACS y SciELO en marzo 2014, mediante descriptores controlados en ciencias de la salud: "la educación, la salud y la información", que comprende seis etapas. Resultados: se encontraron 365 artículos y después de aplicar los criterios de inclusión y exclusión se mantuvieron cuatro. En estas publicaciones fueron mencionadas como una práctica de charlas acerca de la educación para la salud, acciones en eventos festivos, la creación de grupos de coexistencia y las prácticas corporales, directrices acerca del cuidado de las enfermedades crónicas y durante el embarazo.(AU)
Assuntos
Humanos , Masculino , Feminino , Equipe de Assistência ao Paciente , Estratégias de Saúde Nacionais , Educação em Saúde , LILACSRESUMO
Objetivo: avaliar a prevalência de alterações posturais em puérperas durante a amamentação. Método:estudo transversal de abordagem quantitativa realizado com 30 puérperas, no período de setembro a outubro de 2015, no Hospital Regional da cidade de Cajazeiras-PB (HRC), no setor de Banco de Leite. O projeto de pesquisa foi aprovado pelo Comitê de Ética em Pesquisa, Protocolo 748.799. Resultados:foram identificadas alterações posturais nas puérperas, principalmente a hipercifose com 66,7%, hiperlordose cervical (11%) e lombar (20%), e escoliose (33,3%), sendo todas ocasionadas devido ao mau posicionamento adotado durante o ato de amamentar. Conclusão:foram observados hábitos posturais errôneos durante a amamentação em todas as puérperas.(AU)
Objective:evaluating the prevalence of postural changes in puerperals during breastfeeding. Method:a cross-sectional study of a quantitative approach conducted with 30 mothers, in the period September-October 2015, at the Regional Hospital in the city of Cajazeiras-PB (HRC), at the Milk Bank sector. The research project was approved by the Research Ethics Committee, Protocol 748.799. Results:postural changes were identified in puerperals, mostly hyperkyphosis with 66,7%, cervical hyperlordosis (11%) and lumbar (20%), and scoliosis (33,3%), all caused by bad positioning adopted during the act of breastfeeding. Conclusion:there were wrong postural habits during breastfeeding in all mothers.(AU)
Objetivo:evaluar la prevalencia de los cambios posturales en las puérperas durante la lactancia. Método:este es un estudio transversal con un enfoque cuantitativo con la participación de 30 madres, en el período septiembre-octubre de 2015, en el Hospital Regional de la ciudad de Cajazeiras-PB (HRC), en el sector de Banco de Leche. El proyecto de investigación fue aprobado por el Comité de Ética en la Investigación, Protocolo 748.799. Resultados:se identificaron cambios posturales en las puérperas, sobre todo hipercifosis con 66,7%, hiperlordosis cervical (11%) y lumbar (20%), y la escoliosis (33,3%), todo causado por mal posicionamiento adoptado durante el acto de la lactancia materna. Conclusión:hubo malos hábitos posturales durante la lactancia por todas las madres.(AU)
